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Glossary

Term

Definition

A  
AAT Administrative Appeals Tribunal. Body which provides independent review of a wide range of administrative decisions made by the Australian Government and some non-government bodies
ACC Australian Crime Commission
ACCC Australian Competition and Consumer Commission
ACCI Australian Chamber of Commerce and Industry
ACCORD ACCORD Australasia – previously ACSPA, the Australian Consumer and Speciality Products Association
ACGIH American Conference of Governmental Industrial Hygienists
ACT, the The Commonwealth Industrial Chemicals (Notification and Assessment) Act 1989
ADH alcohol dehydrogenase
ADG Code Australian Dangerous Goods Code
ADI acceptable daily intake
AGD Attorney-General’s Department
AHECC Australian Harmonised Export Commodity Classification
ai active ingredient
AICS Australian Inventory of Chemical Substances. A list of chemical identity data maintained by NICNAS; legal device that distinguishes new from existing chemicals and lists all industrial chemicals in use in Australia between 1 January 1977 and 28 February 1990; includes new assessed chemicals since February 1990
AIOH Australian Institute of Occupational Hygienists
AIP Australian Institute of Petroleum
ALT alanine aminotransferase
AP alkaline phosphatase
APMF Australian Paint Manufacturers’ Federation
APS Australian Public Service. Values articulated in section 10(1) of the Public Service Act 1999; provide the real basis and integrating element to the Australian Public Service, its professionalism, its integrity and its impartial and responsive service to the government of the day
APVMA Australian Pesticides and Veterinary Medicines Authority
AQUIRE aquatic toxicity information retrieval database (US EPA)
ANSI American National Standards Institute
AS Australian Standard
AST aspartate aminotransferase
ASTER assessment tools for the evaluation of risk database (US EPA)
ASTM American Society for Testing of Materials
ATP adenosine triphosphate
Audit Formal review of procedures and practices in relation to obligations under the Act
B  
BAT biologischer arbeitsstoff-tolreanz-wert (biological tolerance value for occupational exposure)
BEI Biological Exposure Index
BOD biochemical oxygen demand
BUN blood urea nitrogen
Business plan, NICNAS Document describing the performance measures and data for NICNAS and how these relate to the NICNAS Strategic Plan
bw bodyweight
C  
Candidate list List of chemicals selected for possible priority assessment, following a screening process, from chemicals nominated to NICNAS by industry, unions, the public and government
CAS Chemical Abstracts Service
CBI confidential business information
CCPR Codex Committee on Pesticide Residue
cDNA complementary deoxyribonucleic acid
CEC commercial evaluation permit category (NICNAS)
CEF Community Engagement Forum. NICNAS’s consultative group that identifies community concerns about the impact of industrial chemicals on the environment, public health and/or worker health and safety
CEPA Canadian Environmental Protection Act
ChE cholinesterase
Chemical Gazette Government publication, published by NICNAS, under its Act, on the first Tuesday of each month, containing information regarding changes to NICNAS legislation, newly assessed chemicals and the Register of Chemical Introducers
CHO Chinese hamster ovary
CICAD Concise International Chemical Assessment Document. Informative document published under the IPCS that provides a summary of the relevant scientific information concerning the potential effects of a chemical on human health and/or the environment
CMA Chemical Manufacturers Association (US)
CMC critical micelle concentration
CNS central nervous system
COAG Council of Australian Governments
COD chemical oxygen demand
Compliance case  a business entity which has one or more potential contraventions of the Act
conc. concentration
CONCAWE Oil Companies’ European Organisation for Environmental and Public Health Protection
consultancy procurement of external specialists to provide advice and services where NICNAS staff either do not have the expertise or have overriding obligations
CPI cell proliferation index
CPLG Chemicals and Plastics Leadership Group
CSSC Chemicals Standards Sub-Committee of the ASCC
D  
DEH Australian Government Department of the Environment and Heritage
Director The Director of NICNAS
DIISR Australian Government Department of Innovation, Industry, Science and Research (DIISR)
DITR (the former) Australian Government Department of Industry, Tourism and Resources now Australian Government Department of Innovation, Industry, Science and Research (DIISR)
DNA deoxyribonucleic acid
DOC dissolved organic carbon
DoHA Australian Government Department of Health and Ageing
DOL dissolved oxygen level
DPP Director of Public Prosecutions
DSL Domestic Substances List (Canada)
Due diligence level of judgement, care, prudence, determination and activity with which a person would reasonably be expected to perform under particular circumstances
E  
EA Environment Australia
EASE estimation and assessment of substance exposure
EC50 median effective concentration
EC European Community, or European Commission
ECB European Chemicals Bureau
ECD electron capture detection
ECETOC European Centre for Ecotoxicology and Toxicology of Chemicals
EEO Equal Employment Opportunity
EHD estimated human dose
EINECS European Inventory of Existing Commercial Chemical Substances
EIP Early Introduction Permit
ELINCS European List of Notified Chemical Substances
EL50 Effective loading rate resulting in 50% effect
EPA Environmental Protection Agency (US)
EPHC Environment Protection and Heritage Council
ERMA Environmental Risk Management Authority (New Zealand)
ESD Ecologically Sustainable Development using, conserving and enhancing the community’s resources so that ecological processes, on which life depends, are maintained and the total quality of life, now and in the future, can be enhanced
EU European Union
EUP end use product
EUSES European Union system for the evaluation of substances
Existing Chemicals industrial chemicals other than new industrial chemicals
Exposure assessment An evaluation of exposure to a chemical in the environment. The exposure may be orally, by inhalation or through the skin, or any combination of these
F  
FOB functional observation battery
FOI Freedom of Information
FSANZ Food Standards Australia New Zealand
G  
GABA γ-glutamyl transpeptidase
GC gas-chromatography
GC-MS gas-chromatography/mass spectrometry
GGT γ-glutamyl transferase
GLC gas liquid chromatography
GLP good laboratory practice
GPC gel permeation chromatography
GST glutathione S-transferase
GWP global warming potential
H  
Hazard characterisation Evaluates the dose-response relationship for each of the adverse effects caused by a substance. This is the relationship between the dose of a substance and the incidence or probability of a specific adverse effect
Hazard Identification Determines whether a substance (at any dose) can cause an increase in the incidence of adverse effects and the qualitative evaluation of the adverse effects induced
Hb haemoglobin
Hct haematocrit
HCB hexachlorobenzene
HPLC high-performance liquid chromatography
HPV high production volume (chemicals)
HSNO Hazardous Substances and New Organisms
HVIC Australian High Volume Industrial Chemicals list. A list of information regarding chemicals manufactured in and/or imported into Australia in quantities greater than or equal to 1000 tonnes
I  
IARC International Agency for Research on Cancer
ICMM International Council on Mining and Metals
IC(NA) Act Industrial Chemicals (Notification and Assessment) Act 1989
id intradermal
ILO International Labour Organisation
im intramuscular
INC Intergovernmental Negotiating Committee
ip intraperitoneal
iv intravenous
IDLH immediately dangerous to life and health
IGCC Industry Government Consultative Committee. Primary consultative body for industry and government on NICNAS matters; among other things, reviews the utilisation of resources against NICNAS objectives under terms of reference set by the Minister
Industrial chemical chemical that has an industrial use (whether or not it also has other non-industrial uses)
IPCS International Programme on Chemical Safety. Co-operative venture of the World Health Organisation, International Labour Organisation and United Nations Environmental Programme formed with the objective of establishing the scientific basis for the assessment of the risk to human health and the environment from exposure to chemicals and to provide technical assistance to strengthen national capacities for the sound management of chemicals
IUPAC International Union of Pure and Applied Chemistry
IR infrared
ISEE International Society for Environmental Epidemiology
ISO International Standards Organisation
J  
JETOC Japan Chemical Industry Ecology-Toxicology and Information Centre
K  
Koc organic carbon partition coefficient
Kow octanol/water partition coefficient
L  
LC50 median lethal concentration
LD50 median lethal dose
LDH lactate dehydrogenase
LEV local exhaust ventilation
LL50 lethal loading rate resulting in 50% mortality
LLR lethal loading rate
LOAEL lowest observed adverse effect level
LOEL lowest observed effect level
LoREX Low Release/Low Exposure Exemption (US EPA)
LRCC Act, the the Commonwealth Industrial Chemicals (Notification and Assessment) Amendment (Low Regulatory Concern Chemicals) Act 2004
LRCC Low Regulatory Concern Chemicals. Industrial chemicals which could qualify for reduced regulatory input on the basis of a definition of low risk or where regulatory input from elsewhere is sufficient to meet Australian requirements
LTD Limited Notification category (NICNAS)
LVC Low Volume Chemical (NICNAS)
M  
MAK maximale arbeitsplatz-konzentration (maximum workplace concentration)
MAN Mutual Acceptance of Notification
MCH mean corpuscular (or cell) haemoglobin
MCHC mean corpuscular (or cell) haemoglobin concentration
MCV mean corpuscular (or cell) volume
mg/kg bw/d milligram per kilogram bodyweight per day
MMAD mass median aerodynamic diameter
MMT methylcyclopentadienyl manganese tricarbonyl
MOE margin of exposure
MOS margin of safety
MOU Memorandum of Understanding. Agreement between parties that details mutual obligations in relation to services and/or the exchange of information (relating to industrial chemicals)
MRL maximum residue limit
MTD maximum tolerated dose
MS mass spectrometry
MSDS Material Safety Data Sheet. Document that describes the properties and uses of a substance, i.e. identity, chemical and physical properties, health hazard information, precautions for use and safe handling information
N  
NAMW number-average molecular weight
NAPD nicotinamide adenine dinucleotide phosphate
NDSL Non Domestic Substances List (Canada)
NDPSC National Drugs and Poisons Schedule Committee
NEPM National Environment Protection Measures
New chemicals industrial chemicals (including polymers) not listed on the Australian Inventory of Chemical Substances
NHMRC National Health and Medical Research Council
NICNAS National Industrial Chemicals Notification and Assessment Scheme
NIOSH National Institute of Occupational Safety and Health
NMR nuclear magnetic resonance
NOEC no-observed-effect concentration
NOAEL no-observed-adverse-effect level
NOEL no-observed-effect level
NTP National Toxicology Program
ASCC National Occupational Health and Safety Commission
NOTS Notified Toxic Substances
NZERMA New Zealand Environmental Risk Management Authority
O  
OCS Office of Chemical Safety. Part of the TGA Group of Regulators in the Australian Government Department of Health and Ageing and comprises NICNAS; public health risk assessment for veterinary chemicals, pesticides and other environmental chemicals; establishment of public health controls and standards, and the secretariat for, poisons scheduling; and compliance and monitoring of narcotics and other prohibited goods under UN Treaties and the Customs Act
OECD Organisation for Economic Co-operation and Development. Groups 30 member countries sharing a commitment to democratic government and the market economy; plays a prominent role in fostering good governance in the public service and in corporate activity; work covers economic and social issues from macroeconomics, to trade, education, development and science and innovation
OHS (OH&S) Occupational Health and Safety. General area of concern in employment which spans the physiological and psychological needs and well-being of persons engaged in occupations, work-related trauma and death, the prevention of work-related trauma and death, the protection from, or from risk of, work-related trauma and death, and the rehabilitation and retraining of persons who have suffered work-related trauma
OGTR Office of Gene Technology Regulator
OPPTS Office of Prevention, Pesticides and Toxic Substances (US EPA)
OSHA Occupational Safety and Health Administration (US)
Outcome in the context of the Portfolio Budget Statements (PBS), a stated goal for achievement by an organisation
Output In the context of the Portfolio Budget Statements (PBS), a set of activities and products that contribute to the achievement of a stated goal of an organisation (outcome); subject to performance standards
P  
PAA photon activation analysis
PACIA Plastics and Chemicals Industry Association
PBDE Polybrominated diphenylether
PBFR Polybrominated Flame Retardant
PBPK physiologically based pharmacokinetic
PBS Portfolio Budget Statement. Document that details proposed allocation of resources to government outcomes by agencies within a portfolio; facilitates understanding of the proposed appropriations in Appropriation Bills and provides sufficient information, explanation and justification to enable parliament to understand the purpose of each outcome proposed in the Bills
PCV packed cell volume
PEC (1) predicted environmental concentration
PEC (2) see priority existing chemical
PEL permissible exposure limit (US OSHA)
PFAS Perfluoroalkyl sulfonate
PFOA Perfluorooctanoic acid
PFOS Perfluorooctane sulfonate
PIC prior informed consent
pKa dissociation constant
PLC synthetic polymer of low concern (NICNAS)
PMN pre-manufacture notice (US EPA)
PNEC predicted-no-effect concentration
POC particulate organic carbon
POM particulate organic matter
POP (Stockholm Convention on) Persistent Organic Pollutants (Treaty)
ppb parts per billion
PPE personal protective equipment
ppm parts per million
Precursor chemicals chemicals which are known to be used in the manufacture of drug precursors
Priority existing chemical chemical declared by the Minister for assessment under the NICNAS Existing Chemicals Program because its manufacture, handling, storage, use or disposal gives rise or may give rise to an adverse risk to human health and/or the environment
Q  
QSAR quantitative structure-activity relationship
R  
RACI Royal Australian Chemical Institute
RBC red blood cell
Risk The probability or likelihood of harm and the likely extent of the harm
Risk Assessment

A process involving Hazard identification, Hazard characterisation, Exposure assessment and Risk characterisation

Risk characterisation Interprets and integrates the information from the previous steps to provide a practical estimate of risk and to identify any limitations and uncertainties of this estimate
Risk Management Involves integrating the risk assessment results with economic and social factors to identify strategies to minimise or eliminate the identified risk. These strategies are decided after consideration of all available options. Risk management also involves monitoring, evaluating and reviewing the strategies implemented
RNA ribonucleic acid
Rotterdam Convention The Rotterdam Convention on the Prior Informed Consent (PIC) Procedure for Certain Hazardous Chemicals and Pesticides in International Trade, ratified by Australia on 20 May 2004
RSC Review Steering Committee for NICNAS Existing Chemicals Program
RTECS Registry of Toxic Effects of Chemical Substances (US)
S  
sc subcutaneous
SAR structure-activity relationship
SCAA Surface Coatings Association of Australia
SCE sister chromatid exchange
service charter, NICNAS document that spells out the types, levels and standards of service NICNAS clients can expect from the organisation, including details of complaint resolution procedures
SIAM SIDS Initial Assessment Meeting of the OECD
SIAR SIDS Initial Assessment Report. OECD Existing Chemicals Programme report of hazards of a specific industrial chemical based upon an evaluation of an OECD Screening Information Data Set
SIDS Screening Information Data Set. Agreed minimal data set as determined by the OECD that allows for the establishment of the hazards of a specific industrial chemical
SMILES simplified molecular input line entry system
SNIF Summary Notification Interchange Format (EC)
SNUN significant new use notice (US EPA)
SNUR significant new use rule (US EPA)
STD standard notification category (NICNAS)
STEL short-term exposure limit
Stockholm Convention the Stockholm Convention on Persistent Organic Pollutants (POPs), ratified by Australia on 20 May 2004
STP sewage treatment plant
Strategic plan, NICNAS Document that details the strategies NICNAS will use to achieve its stated goals and values for three year periods (e.g. 2002-2005)
SUSDP Standard for the Uniform Scheduling of Drugs and Poisons
T  
TAG Technical Advisory Group
Tier 1, Tier 2, Tier 3 NICNAS Registration levels, each relating to a range of total values for industrial chemicals introduced in a registration year (1 September – 30 August of following year), used in assessing registration charges
TGA, the Therapeutic Goods Administration is a unit of the Australian Department of Health and Ageing
TLV Threshold Limit Value (ACGIH)
TOD total oxygen demand
TSCA Toxic Substances Control Act (US)
TTMRA Trans-Tasman Mutual Recognition Arrangement
TWA time-weighted average (ASCC)
U  
UDS unscheduled DNA synthesis
UK HSE United Kingdom Health and Safety Executive
UNCED United Nations Conference on Environment and Development
UNEP United Nations Environment Program
US EPA United States Environmental Protection Agency
UVCB unknown or variable composition, complex reaction products, biological material
V  
VOC volatile organic compound
v/v volume per volume
W  
w/v weight per volume
w/w weight per weight
WAF water accommodated fraction
WBC white blood cell
WHO World Health Organisation
WSF water soluble fraction
XYZ  
none  

 

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